Journal article

Prospective population-based cohort of inflammatory bowel disease in the biologics era: Disease course and predictors of severity

O Niewiadomski, C Studd, C Hair, J Wilson, NS Ding, N Heerasing, A Ting, J Mcneill, R Knight, J Santamaria, E Prewett, P Dabkowski, D Dowling, S Alexander, B Allen, B Popp, W Connell, P Desmond, S Bell

Journal of Gastroenterology and Hepatology Australia | Published : 2015

Abstract

Background and Aim: We have previously found high incidence of inflammatory bowel disease (IBD) in Australia. A population-based registry was established to assess disease severity, frequency of complications, and prognostic factors. Methods: Incident cases were prospectively identified over 4 years. Early disease severity was assessed according to need for hospitalization and resective surgery and medication use. Results: We report on the early outcomes (median 18 months, range 12-60 months) for 252 patients comprising 146 with Crohn's disease (CD), 96 with ulcerative colitis (UC), and 10 IBD undifferentiated. Eighty-seven percent of CD patients had inflammatory disease at diagnosis, and th..

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University of Melbourne Researchers