Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis
Andrew J O'Brien, Linda A Villani, Lindsay A Broadfield, Vanessa P Houde, Sandra Galic, Giovanni Blandino, Bruce E Kemp, Theodoros Tsakiridis, Paola Muti, Gregory R Steinberg
Biochemical Journal | PORTLAND PRESS LTD | Published : 2015
Awarded by Canadian Institutes of Health Research
Awarded by Canadian Cancer Society
Awarded by Australian Research Council
Awarded by National Health and Medical Research Council
This work was supported by the Canadian Institutes of Health Research [grant number MOP-11480 (to G.R.S. and T.T.)]; the Canadian Cancer Society [grant number P#20001191 (to G.R.S. and P.M.)]; the Australian Research Council [grant number DP130104548 (to G.R.S., B.E.K. and S.G.)]; the National Health and Medical Research Council [grant number APP1085460 (to G.R.S., B.E.K. and S.G.)]; and the Victorian Government's Operational Infrastructure Support Program.