Journal article

Potentially Modifiable Factors Associated with Death of Infants and Children with Severe Pneumonia Routinely Managed in District Hospitals in Malawi

Penelope M Enarson, Robert P Gie, Charles C Mwansambo, Alfred E Chalira, Norman N Lufesi, Ellubey R Maganga, Donald A Enarson, Neil A Cameron, Stephen M Graham

PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2015

Abstract

OBJECTIVE: To investigate recognised co-morbidities and clinical management associated with inpatient pneumonia mortality in Malawian district hospitals. METHODS: Prospective cohort study, of patient records, carried out in Malawi between 1st October 2000 and 30th June 2003. The study included all children aged 0-59 months admitted to the paediatric wards in sixteen district hospitals throughout Malawi with severe and very severe pneumonia. We compared individual factors between those that survived (n = 14 076) and those that died (n = 1 633). RESULTS: From logistic regression analysis, predictors of death in hospital, adjusted for age, sex and severity grade included comorbid conditions of ..

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Grants

Awarded by Bill and Melinda Gates Foundation


Funding Acknowledgements

The CLHP was primarly funded by the MoH of Malawi, who contributed 69% of the running costs comprising facilities and human resources that are part of the existing health system. The Bill and Melinda Gates Foundation funded the remaining 31% of the costs, 21% of which was investment and 79% operating costs. The Bill & Melinda Gates Foundation grant ID#: 413 http://www.gatesfoundation.org/Pages/home.aspx). The external funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.