Journal article

Mental health starts with physical health: current status and future directions of non-pharmacological interventions to improve physical health in first-episode psychosis

Jesse Gates, Eoin Killackey, Lisa Phillips, Mario Alvarez-Jimenez

The Lancet Psychiatry | ELSEVIER SCI LTD | Published : 2015


People with psychotic disorders have reduced life expectancy compared with the general population. This difference is primarily due to increased prevalence of cardiovascular disease associated with antipsychotic drugs and with modifiable risk factors, including weight gain, low exercise, poor diet, and high prevalence of cigarette smoking. We review non-pharmacological interventions for physical health behaviour in patients with chronic and first-episode psychosis. Our findings suggest that weight loss and attenuation of weight gain are achievable but limited and might not persist beyond the end of an intervention. Evidence for smoking cessation interventions is scarce. The case for early in..

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Funding Acknowledgements

The PhD candidature for JG is supported by an Australian Postgraduate Award scholarship. MA-J is supported by a CR Roper Fellowship, funded by the Faculty of Medicine, Dentistry and Health Sciences at the University of Melbourne. EK is funded by the National Health and Medical Research Council Career Development Fellowship. EK and MA-J work for Orygen, which receives funding from the Australian Federal Government and the Colonial Foundation. LP declares no competing interests.