Journal article
Development and validation of an epidemiologic case definition of epilepsy for use with routinely collected Australian health data
M Tan, I Wilson, V Braganza, S Ignatiadis, R Boston, V Sundararajan, MJ Cook, WJ D'Souza
Epilepsy and Behavior | Published : 2015
Abstract
Objectives: We report the diagnostic validity of a selection algorithm for identifying epilepsy cases. Study design and setting: Retrospective validation study of International Classification of Diseases 10th Revision Australian Modification (ICD-10AM)-coded hospital records and pharmaceutical data sampled from 300 consecutive potential epilepsy-coded cases and 300 randomly chosen cases without epilepsy from 3/7/2012 to 10/7/2013. Two epilepsy specialists independently validated the diagnosis of epilepsy. A multivariable logistic regression model was fitted to identify the optimum coding algorithm for epilepsy and was internally validated. Results: One hundred fifty-eight out of three hundre..
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Funding Acknowledgements
Assoc. Prof. D'Souza has received travel, investigator-initiated, and speaker honoraria and has served on scientific advisory boards from UCB Pharma; has received educational grants from Novartis Pharmaceuticals, Pfizer Pharmaceuticals, and Sanofi-Synthelabo; has received educational, travel, and fellowship grants from GSK Neurology Australia; has served on scientific advisory boards; and has received honoraria from SciGen Pharmaceuticals. His institute has received research funding from GlaxoSmithKline, Scigen, Pfizer, Novartis, and UCB Pharma. The remaining authors have no conflict of interest.