Journal article

Synaptic transmission in the neocortex during reversible cooling

M Volgushev, TR Vidyasagar, M Chistiakova, UT Eysel

Neuroscience | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2000

Abstract

We studied the effects of reversible cooling on synaptic transmission in slices of rat visual cortex. Cooling had marked monotonic effects on the temporal properties of synaptic transmission. It increased the latency of excitatory postsynaptic potentials and prolonged their time-course. Effects were non-monotonic on other properties, such as amplitude of excitatory postsynaptic potentials and generation of spikes. The amplitude of excitatory postsynaptic potentials increased, decreased, or remain unchanged while cooling down to about 20 degrees C, but thereafter it declined gradually in all cells studied. The effect of moderate cooling on spike generation was increased excitability, most pro..

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