Prion protein "gamma-cleavage": characterizing a novel endoproteolytic processing event
Victoria Lewis, Vanessa A Johanssen, Peter J Crouch, Genevieve M Klug, Nigel M Hooper, Steven J Collins
Cellular and Molecular Life Sciences | SPRINGER BASEL AG | Published : 2016
Related Projects (4)
Determining Normal Prion Protein Function, Emphasising The Role Played By Protein Cleavage, And Also Defining The Relationship Between Surveillance Intensity And Annual Sporadic Cjd Incidence
As a neurologist undertaking research into prion diseases over an extended period, I have been able to lead and participate in many projects..
Awarded by Australian Government National Health and Medical Research Council (NHMRC)
Awarded by Medical Research Council of Great Britain
Awarded by Medical Research Council
The authors thank Associate Professor Victoria Lawson for her kind gift of the RK13 cells, Professor Charles Weissmann for the Tga20 mice, and the Victorian Brain Bank Network for their assistance in human control brain tissue sampling. This work was supported by an Australian Government National Health and Medical Research Council (NHMRC) Program Grant #628946 (SJC, VL, VJ), Practitioner Fellowship #1005816 (SJC), Training Fellowship #567123 (VL), R. D. Wright Fellowship (CDF2) (PJC) and Project Grant #1061550 (PJC), a University of Melbourne Early Career Researcher Fellowship (VL), the CJD Support Group Network (VL), and the Medical Research Council of Great Britain (G0802189) (NMH).