The Prototypic Cyclotide Kalata B1 Has a Unique Mechanism of Entering Cells
Sonia Troeira Henriques, Yen-Hua Huang, Stephanie Chaousis, Marc-Antoine Sani, Aaron G Poth, Frances Separovic, David J Craik
Chemistry & Biology | CELL PRESS | Published : 2015
Awarded by Australian Research Council
Awarded by National Health and Medical Research Council
Awarded by NHMRC
S.T.H. is supported by a Discovery Early Career Research Award (grant ID DE120103152) from the Australian Research Council. D.J.C. is a National Health and Medical Research Council Professorial Fellow (grant ID APP1026501). Dr. Oleksiy Kovtun (IMB, UQ) is acknowledged for the help in the preparation of the GVs. Confocal microscopy imaging was performed at the Australian Cancer Research Foundation (ACRF)/IMB Dynamic Imaging Facility for Cancer Biology established with support of ACRF. We thank John Griffin (IMB, UQ) for technical assistance with confocal microscopy imaging. We thank Olivier Cheneval (IMB, UQ) and Phillip Walsh (IMB, UQ) for assistance in peptide synthesis and purification, and Dr. Nicole Lawrence (IMB, UQ) for assistance with cell culture and bioassays. NHMRC is acknowledged for funding this project (grant ID APP1084965).