Journal article

Family History in Young Patients With Stroke

Vincent Thijs, Ulrike Grittner, Martin Dichgans, Christian Enzinger, Franz Fazekas, Anne-Katrin Giese, Christof Kessler, Edwin Kolodny, Peter Kropp, Peter Martus, Bo Norrving, Erich Bernd Ringelstein, Peter M Rothwell, Reinhold Schmidt, Christian Tanislav, Turgut Tatlisumak, Bettina von Sarnowski, Arndt Rolfs

Stroke | LIPPINCOTT WILLIAMS & WILKINS | Published : 2015


BACKGROUND AND PURPOSE: Family history of stroke is an established risk factor for stroke. We evaluated whether family history of stroke predisposed to certain stroke subtypes and whether it differed by sex in young patients with stroke. METHODS: We used data from the Stroke in Fabry Patients study, a large prospective, hospital-based, screening study for Fabry disease in young patients (aged <55 years) with stroke in whom cardiovascular risk factors and family history of stroke were obtained and detailed stroke subtyping was performed. RESULTS: A family history of stroke was present in 1578 of 4232 transient ischemic attack and ischemic stroke patients (37.3%). Female patients more often ha..

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Awarded by Shire Human Genetic Therapies

Awarded by National Institute for Health Research

Funding Acknowledgements

Dr Thijs is supported by a Clinical Research Investigatorship from Scientific Research Fund (FWO) Flanders. The SIFAP study (; No. NCT00414583) has been supported partially by an unrestricted scientific grant from Shire Human Genetic Therapies.