Clinically Relevant Depressive Symptoms in Young Stroke Patients - Results of the sifap1 Study
Christian Tanislav, Peter Kropp, Ulrike Grittner, Martin Holzhausen, Franz Fazekas, Gerhard Jan Jungehuelsing, Turgut Tatlisumak, Bettina von Sarnowski, Jukka Putaala, Roman Huber, Vincent Thijs, Reinhold Schmidt, Manfred Kaps, Christian Enzinger, Martin Dichgans, Bo Norrving, Arndt Rolfs
Neuroepidemiology | KARGER | Published : 2015
BACKGROUND: Although post-stroke depression is widely recognized, less is known about depressive symptoms in the acute stage of stroke and especially in young stroke patients. We thus investigated depressive symptoms and their determinants in such a cohort. METHODS: The Stroke in Young Fabry Patients study (sifap1) prospectively recruited a large multinational European cohort (n = 5,023) of patients with a cerebrovascular event aged 18-55. For assessing clinically relevant depressive symptoms (CRDS, defined by a BDI-score ≥18) the self-reporting Beck Depression Inventory (BDI) was obtained on inclusion in the study. Associations with baseline parameters, stroke severity (National Institutes ..View full abstract
Awarded by Shire Human Genetic Therapies
The sifap 1 study (Stroke in Young Fabry Patients, www.sifap.eu, www.dinicaltrials.gov: No. NCT00414583) has been supported partially by an unrestricted scientific grant from Shire Human Genetic Therapies. The sponsors of the study had no role in the study design, data collection, data analysis, interpretation, writing of the manuscript, or the decision to submit the manuscript for publication.