Journal article

Time is brain(stem) in Basilar artery occlusion

MDI Vergouwen, A Algra, T Pfefferkorn, C Weimar, CM Rueckert, V Thijs, L Jaap Kappelle, WJ Schonewille

Stroke | Published : 2012

Abstract

Background and Purpose-The frequent use of a longer time window for recanalization therapy in patients with basilar artery occlusion (BAO) in daily practice is not supported by any scientific evidence. We investigated the relationship between time to recanalization therapy and functional outcome in BAO with data from the BasilarArtery International Cooperation Study (BASICS). Methods-BASICS is a prospective multicenter registry of patients (n=619) with radiologically confirmed BAO. We analyzed patients receiving intravenous thrombolysis or intra-arterial treatment. Patients were divided into 4 groups based on the interval between estimated time of BAO and start of recanalization therapy: ≤3 ..

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University of Melbourne Researchers