Clinical characteristics of polycystic ovary syndrome: investigating differences in White and South Asian women
Hamidreza Mani, Melanie J Davies, Danielle H Bodicoat, Miles J Levy, Laura J Gray, Trevor A Howlett, Kamlesh Khunti
Clinical Endocrinology | WILEY | Published : 2015
OBJECTIVE: To understand the phenotypic presentation of women with polycystic ovary syndrome (PCOS) of different ethnicities and at different ages. DESIGN: Cross-sectional, retrospective data analysis (1988 - 2009). SETTING: Specialist clinic in a University Hospital, Leicestershire, UK. PARTICIPANTS: Women with PCOS, n = 1310 (mean age 26·2 years), 70·9% White and 29·1% South Asian (SA) attending a speciality clinic in Leicester UK. MAIN OUTCOMES MEASURES: Clinical and demographic characteristics of women with PCOS including age at first clinic appointment, signs and symptoms, body mass index (BMI) and blood pressure (BP). RESULTS: Compared to White women, the SA were younger (24·3 vs 27·1 ..View full abstract
Awarded by National Institute for Health Research
This study was partly funded by 'Early Career Grant' from Society for Endocrinology (HM) and University Hospitals of Leicester NHS Trust Charitable Funds(TAH). The study was part of a PhD project (HM) which has also been supported by Diabetes Research Centre, University of Leicester. Authors acknowledge the help from Dr Hanna Blackledge (HB) in linking two databases used in the original research study. Authors acknowledge the support from the National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care - East Midlands (NIHR CLAHRC - EM), the Leicester Clinical Trials Unit and the NIHR Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit which is a partnership between University Hospitals of Leicester NHS Trust, Loughborough University and the University of Leicester. The views expressed are those of the authors and not necessarily those of the NHS, the named universities, NIHR or the Department of Health.