Journal article
Are all oscillators created equal? in vitro performance characteristics of eight high-frequency oscillatory ventilators
DG Tingay, J John, ER Harcourt, D Black, PA Dargaville, JF Mills, PG Davis
Neonatology | Published : 2015
DOI: 10.1159/000431216
Abstract
Background: The mode of waveform generation and circuit characteristics differ between high-frequency oscillators. It is unknown if this influences performance. Objectives: To describe the relationships between set and delivered pressure amplitude (ΔP), and the interaction with frequency and endotracheal tube (ETT) diameter, in eight high-frequency oscillators. Methods: Oscillators were evaluated using a 70-ml test lung at 1.0 and 2.0 ml/cm H2O compliance, with mean airway pressures (PAW) of 10 and 20 cm H2O, frequencies of 5, 10 and 15 Hz, and an ETT diameter of 2.5 and 3.5 mm. At each permutation of PAW, frequency and ETT, the set ΔP was sequentially increased from 15 to 50 cm H2O, or from..
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Awarded by National Health and Medical Research Council Clinical Research Fellowship
Funding Acknowledgements
D.G.T. is supported by a National Health and Medical Research Council Clinical Research Fellowship (Grant ID 491286). D.G.T., D.B., J.F.M. and P.G.D. are supported by the Victorian Government Operational Infrastructure Support Program. In the last 5 years the research laboratory at Murdoch Childrens Research Institute (D.G.T., P.A.D., J.F.M. and D.B.) have used the SLE5000, SM3100B and BL8000 devices, which were all donated by manufacturers under unrestricted arrangements. D.G.T., P.A.D. and P.G.D. have been authors on peer-reviewed publications performed at other research laboratories in which the BL8000 and SM3100A have been donated (unrestricted). At the time this study was undertaken the Royal Children's Hospital (D.G.T., J.F.M. and E.R.H.) had the SM3100A and B, SLE5000, BL8000, and Sophie devices in clinical usage, the Royal Women's Hospital (P.G.D. and J.J.) the BL8000, VN500 and SM3100A, and the Royal Hobart Hospital (P.A.D.) the BL8000 and SM3100A and B. No author has received consultancy fees from any ventilator manufacturer. D.G.T. has received travel and accommodation (unrestricted) support to speak at workshops sponsored by SLE, CareFusion and Drager in the last 5 years. P.G.D. has received travel and accommodation (unrestricted) support from Fisher & Paykel Healthcare (New Zealand) to attend conferences and workshops as an invited speaker. D.G.T., J.F.M. and P.A.D. have co-convened HFOV educational workshops at the Royal Children's Hospital/Murdoch Childrens Research Institute in which all nine ventilators reported in this study have been demonstrated without any financial, sponsorship or in kind arrangements with any manufacturer.