TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes
Divya Ramnath, Kathryn Tunny, Daniel M Hohenhaus, Claire M Pitts, Anne-Sophie Bergot, P Mark Hogarth, John A Hamilton, Ronan Kapetanovic, Richard A Sturm, Glen M Scholz, Matthew J Sweet
Immunology and Cell Biology | NATURE PUBLISHING GROUP | Published : 2015
Awarded by National Health and Medical Research Council of Australia (NHMRC)
Awarded by NHMRC
Awarded by Australian Research Council DECRA Fellowship
We thank Dr Makrina Totsika and Dr Timothy Barnett for providing some of the cell lines used in this study, the Russell Medical Centre (Brisbane, Queensland) for providing samples used for primary keratinocyte isolation, the Australian Red Cross for the supply of buffy coats used for human monocyte isolation, Professor Ian Frazer for provision of reagents, and Dr Bruce Wines for critical review of this manuscript. This work was supported by a National Health and Medical Research Council of Australia (NHMRC) project grant (ID628769) to GMS, MJS and JAH. MJS is supported by an NHMRC Senior Research Fellowship (APP1003470), RAS is supported by an NHMRC Senior Research Fellowship (APP1043187), and RK is supported by an Australian Research Council DECRA Fellowship (DE1310470).