Effect of flavonoids on remineralization of artificial root caries

Abstract

BACKGROUND: This study compared the effects of three flavonoids, including proanthocyanidin, naringin and quercetin on remineralization of artificial root caries. METHODS: Demineralized root fragments (n = 75) were randomly divided into five groups for treatment with the remineralizing agents for 10 minutes: (1) 6.5% proanthocyanidin; (2) 6.5% naringin; (3) 6.5% quercetin; (4) 1000 ppm fluoride; and (5) deionized water (control). The demineralized samples were pH-cycled through treatment solutions, acidic buffer and neutral buffer for eight days at six cycles per day. The remineralization effects were evaluated using Knoop microhardness, transverse microradiography (lesion depth and mineral ..