Journal article

MAOA-L carriers are better at making optimal financial decisions under risk

Cary Frydman, Colin Camerer, Peter Bossaerts, Antonio Rangel

Proceedings of the Royal Society B | ROYAL SOC | Published : 2011

Abstract

Genes can affect behaviour towards risks through at least two distinct neurocomputational mechanisms: they may affect the value assigned to different risky options, or they may affect the way in which the brain adjudicates between options based on their value. We combined methods from neuroeconomics and behavioural genetics to investigate the impact that the genes encoding for monoamine oxidase-A (MAOA), the serotonin transporter (5-HTT) and the dopamine D4 receptor (DRD4) have on these two computations. Consistent with previous literature, we found that carriers of the MAOA-L polymorphism were more likely to take financial risks. Our computational choice model, rooted in established decisio..

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University of Melbourne Researchers