Chris Bye

Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain

Christopher R Bye, Vanessa Penna, Isabelle R de Luzy, Carlos W Gantner, Cameron PJ Hunt, Lachlan H Thompson, Clare L Parish

Journal article  |  2019  |  Stem Cell Reports

Human pluripotent stem cells are a valuable resource for transplantation, yet our ability to profile xenografts is largely limited..

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins

Christopher R Bye, Valeria Rytova, Walaa F Alsanie, Clare L Parish, Lachlan H Thompson

Journal article  |  2019  |  Journal of Neuroscience

The growth of axons corresponding to different neuronal subtypes is governed by unique expression profiles of molecules on the gro..

Association of Regulatory T-Cell Expansion With Progression of Amyotrophic Lateral Sclerosis A Study of Humans and a Transgenic Mouse Model

Rebecca K Sheean, Fiona C McKay, Erika Cretney, Christopher R Bye, Nirma D Perera, Doris Tomas, Richard A Weston, Karlene J Scheller, Elvan Djouma, Parvathi Menon, Stephen D Schibeci, Najwa Marmash, Justin J Yerbury, Stephen L Nutt, David R Booth, Graeme J Stewart, Mathew C Kiernan, Steve Vucic, Bradley J Turner

Journal article  |  2018  |  JAMA Neurology

Specification of murine ground state pluripotent stem cells to regional neuronal populations

Walaa F Alsanie, Jonathan C Niclis, Cameron P Hunt, Isabelle R De Luzy, Vanessa Penna, Christopher R Bye, Colin W Pouton, John Haynes, Jaber Firas, Lachlan H Thompson, Clare L Parish

Journal article  |  2017  |  Scientific Reports

Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno-Free Conditions Restore Motor Deficits in Parkinsonian Rodents

Jonathan C Niclis, Carlos W Gantner, Walaa F Alsanie, Stuart J McDougall, Chris R Bye, Andrew G Elefanty, Edouard G Stanley, John M Haynes, Colin W Pouton, Lachlan H Thompson, Clare L Parish

Journal article  |  2017  |  Stem Cells Translational Medicine

Meningeal cells influence midbrain development and the engraftment of dopamine progenitors in Parkinsonian mice

Fahad A Somaa, Christopher R Bye, Lachlan H Thompson, Clare L Parish

Journal article  |  2015  |  Experimental Neurology

Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors

Chris R Bye, Marie E Jonsson, Anders Bjorklund, Clare L Parish, Lachlan H Thompson

Journal article  |  2015  |  Proceedings of the National Academy of Sciences of the United States of America

Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease

Helene Hall, Stefanie Reyes, Natalie Landeck, Chris Bye, Giampiero Leanza, Kay Double, Lachlan Thompson, Glenda Halliday, Deniz Kirik

Journal article  |  2014  |  Brain

Diverse Roles for Wnt7a in Ventral Midbrain Neurogenesis and Dopaminergic Axon Morphogenesis

Chathurini V Fernando, Julianna Kele, Christopher R Bye, Jonathan C Niclis, Walaa Alsanie, Brette D Blakely, Jan Stenman, Brad J Turner, Clare L Parish

Journal article  |  2014  |  Stem Cells and Development

Ryk, a Receptor Regulating Wnt5a-Mediated Neurogenesis and Axon Morphogenesis of Ventral Midbrain Dopaminergic Neurons

Brette D Blakely, Christopher R Bye, Chathurini V Fernando, Asheeta A Prasad, R Jeroen Pasterkamp, Maria L Macheda, Steven A Stacker, Clare L Parish

Journal article  |  2013  |  Stem Cells and Development