William Heath

Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes.

James G Bedford, Melanie Heinlein, Alexandra L Garnham, Thi HO Nguyen, Tom Loudovaris, Chenghao Ge, Stuart I Mannering, Michael Elliott, Stuart G Tangye, Katherine Kedzierska, Daniel HD Gray, William R Heath, Linda M Wakim

Journal article  |  2020  |  Science Immunology

The nasal-associated lymphoid tissues (NALTs) are mucosal-associated lymphoid organs embedded in the submucosa of the nasal passag..

Display of Native Antigen on cDC1 That Have Spatial Access to Both T and B Cells Underlies Efficient Humoral Vaccination.

Yu Kato, Thiago M Steiner, Hae-Young Park, Rohan O Hitchcock, Ali Zaid, Jyh Liang Hor, Sapna Devi, Gayle M Davey, David Vremec, Kirsteen M Tullett, Peck S Tan, Fatma Ahmet, Scott N Mueller, Sylvie Alonso, David M Tarlinton, Hidde L Ploegh, Tsuneyasu Kaisho, Lynette Beattie, Jonathan H Manton, Daniel Fernandez-Ruiz, et al.

Journal article  |  2020  |  The Journal of Immunology

Follicular dendritic cells and macrophages have been strongly implicated in presentation of native Ag to B cells. This property ha..

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

Susanna S Ng, Fabian De Labastida Rivera, Juming Yan, Dillon Corvino, Indrajit Das, Ping Zhang, Rachel Kuns, Shashi Bhushan Chauhan, Jiajie Hou, Xian-Yang Li, Teija CM Frame, Benjamin A McEnroe, Eilish Moore, Jinrui Na, Jessica A Engel, Megan SF Soon, Bhawana Singh, Andrew J Kueh, Marco J Herold, Marcela Montes de Oca, et al.

Journal article  |  2020  |  Nature Immunology

A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver T-RM Cell-Mediated Immunity against Malaria in Mice

Ana Maria Valencia-Hernandez, Wei Yi Ng, Nazanin Ghazanfari, Sonia Ghilas, Maria N de Menezes, Lauren E Holz, Cheng Huang, Kieran English, Myo Naung, Peck Szee Tan, Kirsteen M Tullett, Thiago M Steiner, Matthias H Enders, Lynette Beattie, Yu Cheng Chua, Claerwen M Jones, Anton Cozijnsen, Vanessa Mollard, Yeping Cai, David G Bowen, et al.

Journal article  |  2020  |  Cell Host & Microbe

Liver-resident memory CD8+ T (TRM) cells remain in and constantly patrol the liver to elicit rapid immunity upon antigen encounter..

Glycolipid-peptide vaccination induces liver-resident memory CD8( ) T cells that protect against rodent malaria

Lauren E Holz, Yu Cheng Chua, Maria N de Menezes, Regan J Anderson, Sarah L Draper, Benjamin J Compton, Susanna TS Chan, Juby Mathew, Jasmine Li, Lukasz Kedzierski, Zhongfang Wang, Lynette Beattie, Matthias H Enders, Sonia Ghilas, Rose May, Thiago M Steiner, Joshua Lange, Daniel Fernandez-Ruiz, Ana Maria Valencia-Hernandez, Taryn L Osmond, et al.

Journal article  |  2020  |  Science Immunology

Liver resident-memory CD8+ T cells (TRM cells) can kill liver-stage Plasmodium-infected cells and prevent malaria, but simple vacc..

Raster Adaptive Optics for Video Rate Laser Scanning Microscopy with Large Field of View Correction

Y Li, YJ Lim, Q Xu, L Beattie, EE Gardiner, K Gaus, WR Heath, WM Lee

Conference Proceedings  |  2020  |  Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS

Raster adaptive optics for video rate aberration correction and large FOV multiphoton imaging

Yongxiao Li, Yean J Lim, Qiongkai Xu, Lynette Beattie, Elizabeth E Gardiner, Katharina Gaus, William R Heath, Woei Ming Lee

Journal article  |  2020  |  Biomedical Optics Express

Visualizing MHC-II restricted response to rodent malaria.

M Enders, L Beattie, D Fernandez Ruiz, E Mass, WR Heath

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Antigen presentation by dendritic cells for B cell activation

William R Heath, Yu Kato, Thiago M Steiner, Irina Caminschi

Journal article  |  2019  |  Current Opinion in Immunology

Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection

Christopher M Harpur, Yu Kato, Shinta T Dewi, Sanda Stankovic, Darryl N Johnson, Sammy Bedoui, Paul G Whitney, Mireille H Lahoud, Irina Caminschi, William R Heath, Andrew G Brooks, Thomas Gebhardt

Journal article  |  2019  |  The Journal of Immunology