James Vince

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection.

Marcel Doerflinger, Yexuan Deng, Paul Whitney, Ranja Salvamoser, Sven Engel, Andrew J Kueh, Lin Tai, Annabell Bachem, Elise Gressier, Niall D Geoghegan, Stephen Wilcox, Kelly L Rogers, Alexandra L Garnham, Michael A Dengler, Stefanie M Bader, Gregor Ebert, Jaclyn S Pearson, Dominic De Nardo, Nancy Wang, Chenying Yang, et al.

Journal article  |  2020  |  Immunity

Programmed cell death contributes to host defense against pathogens. To investigate the relative importance of pyroptosis, necropt..

Inflammasomes and Cell Death: Common Pathways in Microparticle Diseases.

Maryam Rashidi, Ian P Wicks, James E Vince

Journal article  |  2020  |  Trends in Molecular Medicine

The accumulation of cellular and environmental microparticles has been linked to many diseases associated with tissue inflammation..

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma

Sarah A Best, Sheryl Ding, Ariena Kersbergen, Xueyi Dong, Ji-Ying Song, Yi Xie, Boris Reljic, Kaiming Li, James E Vince, Vivek Rathi, Gavin M Wright, Matthew E Ritchie, Kate D Sutherland

Journal article  |  2019  |  Nature Communications

The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1 beta Release

Maryam Rashidi, Daniel S Simpson, Anne Hempel, Daniel Frank, Emma Petrie, Angelina Vince, Rebecca Feltham, Jane Murphy, Simon M Chatfield, Guy S Salvesen, James M Murphy, Ian P Wicks, James E Vince

Journal article  |  2019  |  The Journal of Immunology

The pyroptotic cell death effector gasdermin D (GSDMD) is required for murine models of hereditary inflammasome-driven, IL-1β-depe..

RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development

Holly Anderton, Esther Bandala-Sanchez, Daniel S Simpson, James A Rickard, Ashley P Ng, Ladina Di Rago, Cathrine Hall, James E Vince, John Silke, Gianmaria Liccardi, Rebecca Feltham

Journal article  |  2019  |  Cell Death & Differentiation

Macrophages, rather than DCs, are responsible for inflammasome activity in the GM-CSF BMDC model

Ziv Erlich, Inbar Shlomovitz, Liat Edry-Botzer, Hadar Cohen, Daniel Frank, Hanging Wang, Andrew M Lew, Kate E Lawlor, Yifan Zhan, James E Vince, Motti Gerlic

Journal article  |  2019  |  Nature Immunology

Activated MLKL attenuates autophagy following its translocation to intracellular membranes

Daniel Frank, David L Vaux, James M Murphy, James E Vince, Lisa M Lindqvist

Journal article  |  2019  |  Journal of Cell Science

Pyroptosis versus necroptosis: similarities, differences, and crosstalk

Daniel Frank, James E Vince

Journal article  |  2019  |  Cell Death & Differentiation

Padi4 Regulates NET Formation and Inflammatory Cell Death Downstream of Mlkl

Akshay A D'Cruz, Mary Speir, Meghan Bliss-Moreau, Sylvia Dietrich, Alyce A Chen, Mathilde Gavillet, Kate E Lawlor, James E Vince, Michelle Kelliher, Razq Hakem, Manolis Pasparakis, David A Williams, Maria Ericsson, Ben A Croker

Conference Proceedings  |  2018  |  Blood

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and-7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1 beta Activation

James E Vince, Dominic De Nardo, Wenqing Gao, Angelina J Vince, Cathrine Hall, Kate McArthur, Daniel Simpson, Swarna Vijayaraj, Lisa M Lindqvist, Philippe Bouillet, Mark A Rizzacasa, Si Ming Man, John Silke, Seth L Masters, Guillaume Lessene, David CS Huang, Daniel HD Gray, Benjamin T Kile, Feng Shao, Kate E Lawlor

Journal article  |  2018  |  Cell Reports

Ion Man: GSDMD Punches Pores to Knock Out cGAS

Rebecca Feltham, James E Vince

Journal article  |  2018  |  Immunity

The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils

Akshay A D'Cruz, Mary Speir, Meghan Bliss-Moreau, Sylvia Dietrich, Shu Wang, Alyce A Chen, Mathilde Gavillet, Arshed Al-Obeidi, Kate E Lawlor, James E Vince, Michelle A Kelliher, Razq Hakem, Manolis Pasparakis, David A Williams, Maria Ericsson, Ben A Croker

Journal article  |  2018  |  Science Signaling

Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-beta Secretion

Kaiwen W Chen, Kate E Lawlor, Jessica B von Pein, Dave Boucher, Motti Gerlic, Ben A Croker, Jelena S Bezbradica, James E Vince, Kate Schroder

Journal article  |  2018  |  The Journal of Immunology

Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications

Arpeeta Sharma, Mitchel Tate, Geetha Mathew, James E Vince, Rebecca H Ritchie, Judy B de Haan

Journal article  |  2018  |  Frontiers in Physiology

CD52 inhibits Toll-like receptor activation of NF-kappa B and triggers apoptosis to suppress inflammation

Maryam Rashidi, Esther Bandala-Sanchez, Kate E Lawlor, Yuxia Zhang, Alana M Neale, Swarna L Vijayaraj, Robert O'Donoghue, John M Wentworth, Timothy E Adams, James E Vince, Leonard C Harrison

Journal article  |  2018  |  Cell Death & Differentiation

Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8

Vitaliya Sagulenko, Nazarii Vitak, Parimala R Vajjhala, James E Vince, Katryn J Stacey

Journal article  |  2018  |  Journal of Molecular Biology

Simultaneous Detection of Cellular Viability and Interleukin-1β Secretion from Single Cells by ELISpot.

Stephanie A Conos, Lisa M Lindqvist, James E Vince

Journal article  |  2018  |  Methods in molecular biology (Clifton, N.J.)

Cell death results in the breakdown of the plasma membrane, which can cause the release of cytosolic proteins. During caspase-1-me..

Pyroptosis

KE Lawlor, S Conos, JE Vince

Book Chapter  |  2018

XIAP Loss Triggers RIPK3-and Caspase-8-Driven IL-1 beta Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation

Kate E Lawlor, Rebecca Feltham, Monica Yabal, Stephanie A Conos, Kaiwen W Chen, Stephanie Ziehe, Carina Grass, Yifan Zhan, Tan A Nguyen, Cathrine Hall, Angelina J Vince, Simon M Chatfield, Damian B D'Silva, Kenneth C Pang, Kate Schroder, John Silke, David L Vaux, Philipp J Jost, James E Vince

Journal article  |  2017  |  Cell Reports

POSTTRANSLATIONAL MODIFICATION AS A CRITICAL DETERMINANT OF CYTOPLASMIC INNATE IMMUNE RECOGNITION

Paul J Baker, Dominic De Nardo, Fiona Moghaddas, Son Tran Le, Annabell Bachem, Nguyen Tan, Thomas Hayman, Hazel Tye, James E Vince, Sammy Bedoui, Richard L Ferrero, Seth L Masters

Journal article  |  2017  |  Physiological Reviews

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

Jaclyn S Pearson, Cristina Giogha, Sabrina Muhlen, Ueli Nachbur, Chi LL Pham, Ying Zhang, Joanne M Hildebrand, Clare V Oates, Tania Wong Fok Lung, Danielle Ingle, Laura F Dagley, Aleksandra Bankovacki, Emma J Petrie, Gunnar N Schroeder, Valerie F Crepin, Gad Frankel, Seth L Masters, James Vince, James M Murphy, Margaret Sunde, et al.

Journal article  |  2017  |  Nature Microbiology

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation (vol 2, 16258, 2017)

Jaclyn S Pearson, Cristina Giogha, Sabrina Muehlen, Ueli Nachbur, Chi LL Pham, Ying Zhang, Joanne M Hildebrand, Clare V Oates, Tania Wong Fok Lung, Danielle Ingle, Laura F Dagley, Aleksandra Bankovacki, Emma J Petrie, Gunnar N Schroeder, Valerie F Crepin, Gad Frankel, Seth L Masters, James Vince, James M Murphy, Margaret Sunde, et al.

Journal article  |  2017  |  Nature Microbiology

Combination of IAP antagonist and IFN gamma activates novel caspase-10-and RIPK1-dependent cell death pathways

Maria C Tanzer, Nufail Khan, James A Rickard, Nima Etemadi, Najoua Lalaoui, Sukhdeep Kaur Spall, Joanne M Hildebrand, David Segal, Maria Miasari, Diep Chau, WendyWei-Lynn Wong, Mark McKinlay, Srinivas K Chunduru, Christopher A Benetatos, Stephen M Condon, James E Vince, Marco J Herold, John Silke

Journal article  |  2017  |  Cell Death & Differentiation

Legionella pneumophila Strain 130b Evades Macrophage Cell Death Independent of the Effector SidF in the Absence of Flagellin

Mary Speir, Adam Vogrin, Azadeh Seidi, Gilu Abraham, Stephane Hunot, Qingqing Han, Gerald W Dorn, Seth L Masters, Richard A Flavell, James E Vince, Thomas Naderer

Journal article  |  2017  |  Frontiers in Cellular and Infection Microbiology

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner

Stephanie A Conos, Kaiwen W Chen, Dominic De Nardo, Hideki Hara, Lachlan Whitehead, Gabriel Nunez, Seth L Masters, James M Murphy, Kate Schroder, David L Vaux, Kate E Lawlor, Lisa M Lindqvist, James E Vince

Journal article  |  2017  |  Proceedings of the National Academy of Sciences

Necroptotic death signaling: evolution, mechanisms and disease relevance

James E Vince

Journal article  |  2017  |  Immunology & Cell Biology

Caspase-8: not so silently deadly

Rebecca Feltham, James E Vince, Kate E Lawlor

Journal article  |  2017  |  Clinical & Translational Immunology

IAPs and Cell Death

John Silke, James Vince

Book Chapter  |  2017  |  Current Topics in Microbiology and Immunology

Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins

Katharine J Goodall, Megan L Finch-Edmondson, Joanne van Vuuren, George C Yeoh, Ian E Gentle, James E Vince, Paul G Ekert, David L Vaux, Bernard A Callus

Journal article  |  2016  |  PLOS ONE

Cell death is not essential for caspase-1-mediated interleukin-1 beta activation and secretion

SA Conos, KE Lawlor, DL Vaux, JE Vince, LM Lindqvist

Journal article  |  2016  |  Cell Death & Differentiation

Evolutionary divergence of the necroptosis effector MLKL

MC Tanzer, I Matti, JM Hildebrand, SN Young, A Wardak, A Tripaydonis, EJ Petrie, AL Mildenhall, DL Vaux, JE Vince, PE Czabotar, J Silke, JM Murphy

Journal article  |  2016  |  Cell Death & Differentiation

The intersection of cell death and inflammasome activation

James E Vince, John Silke

Journal article  |  2016  |  Cellular and Molecular Life Sciences

Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis

Mary Speir, Kate E Lawlor, Stefan P Glaser, Gilu Abraham, Seong Chow, Adam Vogrin, Keith E Schulze, Ralf Schuelein, Lorraine A O'Reilly, Kylie Mason, Elizabeth L Hartland, Trevor Lithgow, Andreas Strasser, Guillaume Lessene, David CS Huang, James E Vince, Thomas Naderer

Journal article  |  2016  |  Nature Microbiology

New insights into the regulation of innate immunity by caspase-8

Vitaliya Sagulenko, Kate E Lawlor, James E Vince

Journal article  |  2016  |  Arthritis Research & Therapy

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome

Andrew J Murphy, Michael J Kraakman, Helene L Kammoun, Dragana Dragoljevic, Man KS Lee, Kate E Lawlor, John M Wentworth, Ajithkumar Vasanthakumar, Motti Gerlic, Lachlan W Whitehead, Ladina DiRago, Louise Cengia, Rachael M Lane, Donald Metcalf, James E Vince, Leonard C Harrison, Axel Kallies, Benjamin T Kile, Ben A Croker, Mark A Febbraio, et al.

Journal article  |  2016  |  Cell Metabolism

Response to Heard et al

Maryline Moulin, Anne K Voss, Tim Thomas, Wendy Wei-Lynn Wong, Wendy D Cook, Frank Koentgen, James Vince, John Silke, David L Vaux

Journal article  |  2015  |  The EMBO Journal

When Beauty Is Skin Deep: Regulation of the Wound Response by Caspase-8, RIPK3, and the Inflammasome

James E Vince

Journal article  |  2015  |  Journal of Investigative Dermatology

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

Ueli Nachbur, Che A Stafford, Aleksandra Bankovacki, Yifan Zhan, Lisa M Lindqvist, Berthe K Fiil, Yelena Khakham, Hyun-Ja Ko, Jarrod J Sandow, Hendrik Falk, Jessica K Holien, Diep Chau, Joanne Hildebrand, James E Vince, Phillip P Sharp, Andrew I Webb, Katherine A Jackman, Sabrina Muehlen, Catherine L Kennedy, Kym N Lowes, et al.

Journal article  |  2015  |  Nature Communications

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Kate E Lawlor, Nufail Khan, Alison Mildenhall, Motti Gerlic, Ben A Croker, Akshay A D'Cruz, Cathrine Hall, Sukhdeep Kaur Spall, Holly Anderton, Seth L Masters, Maryam Rashidi, Ian P Wicks, Warren S Alexander, Yasuhiro Mitsuuchi, Christopher A Benetatos, Stephen M Condon, W Wei-Lynn Wong, John Silke, David L Vaux, James E Vince

Journal article  |  2015  |  Nature Communications

Post-translational control of RIPK3 and MLKL mediated necroptotic cell death.

James M Murphy, James E Vince

Journal article  |  2015  |  F1000Research

Several programmed lytic and necrotic-like cell death mechanisms have now been uncovered, including the recently described recepto..

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming

Ramanjaneyulu Allam, Kate E Lawlor, Eric Chi-Wang Yu, Alison L Mildenhall, Donia M Moujalled, Rowena S Lewis, Francine Ke, Kylie D Mason, Michael J White, Katryn J Stacey, Andreas Strasser, Lorraine A O'Reilly, Warren Alexander, Benjamin T Kile, David L Vaux, James E Vince

Journal article  |  2014  |  EMBO reports

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

James A Rickard, Joanne A O'Donnell, Joseph M Evans, Najoua Lalaoui, Ashleigh R Poh, TeWhiti Rogers, James E Vince, Kate E Lawlor, Robert L Ninnis, Holly Anderton, Cathrine Hall, Sukhdeep K Spall, Toby J Phesse, Helen E Abud, Louise H Cengia, Jason Corbin, Sandra Mifsud, Ladina Di Rago, Donald Metcalf, Matthias Ernst, et al.

Journal article  |  2014  |  Cell

Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies

Stephen M Condon, Yasuhiro Mitsuuchi, Yijun Deng, Matthew G LaPorte, Susan R Rippin, Thomas Haimowitz, Matthew D Alexander, Pavan Tirunahari Kumar, Mukta S Hendi, Yu-Hua Lee, Christopher A Benetatos, Guangyao Yu, Gurpreet Singh Kapoor, Eric Neiman, Martin E Seipel, Jennifer M Burns, Martin A Graham, Mark A McKinlay, Xiaochun Li, Jiawei Wang, et al.

Journal article  |  2014  |  Journal of Medicinal Chemistry

cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1-and RIPK3-dependent manner

W Wei-Lynn Wong, James E Vince, Najoua Lalaoui, Kate E Lawlor, Diep Chau, Aleksandra Bankovacki, Holly Anderton, Donald Metcalf, Lorraine O'Reilly, Philipp J Jost, James M Murphy, Warren S Alexander, Andreas Strasser, David L Vaux, John Silke

Journal article  |  2014  |  Blood

Ambiguities in NLRP3 inflammasome regulation: Is there a role for mitochondria?

Kate E Lawlor, James E Vince

Journal article  |  2014  |  Biochimica et Biophysica Acta - General Subjects

The Pathogen Candida albicans Hijacks Pyroptosis for Escape from Macrophages

Nathalie Uwamahoro, Jiyoti Verma-Gaur, Hsin-Hui Shen, Yue Qu, Rowena Lewis, Jingxiong Lu, Keith Bambery, Seth L Masters, James E Vince, Thomas Naderer, Ana Traven

Journal article  |  2014  |  MBIO

More to life than death: molecular determinants of necroptotic and non-necroptotic RIP3 kinase signaling

Nufail Khan, Kate E Lawlor, James M Murphy, James E Vince

Journal article  |  2014  |  Current Opinion in Immunology

Programmed cell death in Legionella infection

Mary Speir, James E Vince, Thomas Naderer

Journal article  |  2014  |  Future Microbiology

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC

V Sagulenko, SJ Thygesen, DP Sester, A Idris, JA Cridland, PR Vajjhala, TL Roberts, K Schroder, JE Vince, JM Hill, J Silke, KJ Stacey

Journal article  |  2013  |  Cell Death & Differentiation

Bcl-2 overexpression ameliorates immune complex-mediated arthritis by altering Fc gamma RIIb expression and monocyte homeostasis

Kate E Lawlor, Annemarie van Nieuwenhuijze, Karen L Parker, Sarah F Drake, Ian K Campbell, Scott D Smith, James E Vince, Andreas Strasser, Ian P Wicks

Journal article  |  2013  |  Journal of Leukocyte Biology

TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1

DM Moujalled, WD Cook, T Okamoto, J Murphy, KE Lawlor, JE Vince, DL Vaux

Journal article  |  2013  |  Cell Death & Disease

Is BID required for NOD signalling?

Ueli Nachbur, James E Vince, Lorraine A O'Reilly, Andreas Strasser, John Silke

Journal article  |  2012  |  Nature

Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation

James E Vince, W Wei-Lynn Wong, Ian Gentle, Kate E Lawlor, Ramanjaneyulu Allam, Lorraine O'Reilly, Kylie Mason, Olaf Gross, Stephen Ma, Greta Guarda, Holly Anderton, Rosa Castillo, Georg Haecker, John Silke, Juerg Tschopp

Journal article  |  2012  |  Immunity

IAPs, TNF, inflammation and Jurg TSCHOPP; a personal perspective

J Silke, JE Vince

Journal article  |  2012  |  Cell Death & Differentiation

The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

P Menu, JE Vince

Journal article  |  2011  |  Clinical & Experimental Immunology

Lysosomal degradation of Leishmania hexose and inositol transporters is regulated in a stage-, nutrient- and ubiquitin-dependent manner

James E Vince, Dedreia Tull, Scott Landfear, Malcolm J McConville

Journal article  |  2011  |  International Journal for Parasitology

Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding

Rebecca Feltham, Maryline Moulin, James E Vince, Peter D Mace, Wendy Wei-Lynn Wong, Holly Anderton, Catherine L Day, David L Vaux, John Silke

Journal article  |  2010  |  Journal of Biological Chemistry

IRF-3 partners Bax in a viral-induced dance macarbre

James E Vince, Jurg Tschopp

Journal article  |  2010  |  The EMBO Journal

TAK1 Is Required for Survival of Mouse Fibroblasts Treated with TRAIL, and Does So by NF-kappa B Dependent Induction of cFLIPL

Josep Maria Lluis, Ulrich Nachbur, Wendy Diane Cook, Ian Edward Gentle, Donia Moujalled, Maryline Moulin, Wendy Wei-Lynn Wong, Nufail Khan, Diep Chau, Bernard Andrew Callus, James Edward Vince, John Silke, David Lawrence Vaux

Journal article  |  2010  |  PLoS ONE

TRAF2 Must Bind to Cellular Inhibitors of Apoptosis for Tumor Necrosis Factor (TNF) to Efficiently Activate NF-kappa B and to Prevent TNF-induced Apoptosis

James E Vince, Delara Pantaki, Rebecca Feltham, Peter D Mace, Stephanie M Cordier, Anna C Schmukle, Angelina J Davidson, Bernard A Callus, Wendy Wei-Lynn Wong, Ian E Gentle, Holly Carter, Erinna F Lee, Henning Walczak, Catherine L Day, David L Vaux, John Silke

Journal article  |  2009  |  J. Biol. Chem.

Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

Tobias L Haas, Christoph H Emmerich, Bjoern Gerlach, Anna C Schmukle, Stefanie M Cordier, Eva Rieser, Rebecca Feltham, James Vince, Uwe Warnken, Till Wenger, Ronald Koschny, David Komander, John Silke, Henning Walczak

Journal article  |  2009  |  Molecular Cell

CARP2 deficiency does not alter induction of NF-kappa B by TNF alpha

Afsar U Ahmed, Maryline Moulin, Franck Coumailleau, W Wei-Lynn Wong, Maria Miasari, Holly Carter, John Silke, Michel Cohen-Tannoudji, James E Vince, David L Vaux

Journal article  |  2009  |  Curr. Biol.

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNF alpha

James E Vince, Diep Chau, Bernard Callus, W Wei-Lynn Wong, Christine J Hawkins, Pascal Schneider, Mark McKinlay, Christopher A Benetatos, Stephen M Condon, Srinivas K Chunduru, George Yeoh, Robert Brink, David L Vaux, John Silke

Journal article  |  2008  |  JOURNAL OF CELL BIOLOGY

Cytoplasmic p53 is not required for PUMA-induced apoptosis

BA Callus, PG Ekert, JE Heraud, AM Jabbour, A Kotevski, JE Vince, J Silke, DL Vaux

Journal article  |  2008  |  Cell Death & Differentiation

IAP antagonists target cIAP1 to induce TNF alpha- dependent apoptosis

James E Vince, W Wei-Lynn Wong, Nufail Khan, Rebecca Feltham, Diep Chau, Afsar U Ahmed, Christopher A Benetatos, Srinivas K Chunduru, Stephen M Condon, Mark McKinlay, Robert Brink, Martin Leverkus, Vinay Tergaonkar, Pascal Schneider, Bernard A Callus, Frank Koentgen, David L Vaux, John Silke

Journal article  |  2007  |  Cell

Down-regulation of the trypanosomatid signal recognition particle affects the biogenesis of polytopic membrane proteins but not of signal peptide-containing proteins

Yaniv Lustig, Yaron Vagima, Hanoch Goldshmidt, Avigail Erlanger, Vered Ozeri, James Vince, Malcolm J McConville, Dennis M Dwyer, Scott M Landfear, Shulamit Michaeli

Journal article  |  2007  |  Eukaryotic Cell

TWEAK shall inherit the earth

JE Vince, J Silke

Journal article  |  2006  |  Cell Death & Differentiation

SMP-1, a member of a new family of small myristoylated proteins in kinetoplastid parasites, is targeted to the flagellum membrane in Leishmania

D Tull, JE Vince, JM Callaghan, T Naderer, T Spurck, GI McFadden, G Currie, K Ferguson, A Bacic, MJ McConville

Journal article  |  2004  |  MOLECULAR BIOLOGY OF THE CELL