Michael Roy

BAK core dimers bind lipids and can be bridged by them

Angus D Cowan, Nicholas A Smith, Jarrod J Sandow, Eugene A Kapp, Yepy H Rustam, James M Murphy, Jason M Brouwer, Jonathan P Bernardini, Michael J Roy, Ahmad Z Wardak, Iris K Tan, Andrew I Webb, Jacqueline M Gulbis, Brian J Smith, Gavin E Reid, Grant Dewson, Peter M Colman, Peter E Czabotar

Journal article  |  2020  |  NATURE STRUCTURAL & MOLECULAR BIOLOGY

BAK and BAX are essential mediators of apoptosis that oligomerize in response to death cues, thereby causing permeabilization of t..

The PEAK family of pseudokinases, their role in cell signalling and cancer

Onisha Patel, Michael J Roy, James M Murphy, Isabelle S Lucet

Journal article  |  2019  |  FEBS JOURNAL

The study of pseudokinases has uncovered that catalysis-independent functions play a critical role in cell signalling regulation. ..