Torsten Seemann

Tuberculosis in Australia's tropical north: a population-based genomic epidemiological study.

Ella M Meumann, Kristy Horan, Anna P Ralph, Belinda Farmer, Maria Globan, Elizabeth Stephenson, Tracy Popple, Rowena Boyd, Mirjam Kaestli, Torsten Seemann, Koen Vandelannoote, Christopher Lowbridge, Robert W Baird, Timothy P Stinear, Deborah A Williamson, Bart J Currie, Vicki L Krause

Journal article  |  2021  |  Lancet Reg Health West Pac

Background: The Northern Territory (NT) has the highest tuberculosis (TB) rate of all Australian jurisdictions. We combined TB pub..

Defective Severe Acute Respiratory Syndrome Coronavirus 2 Immune Responses in an Immunocompromised Individual With Prolonged Viral Replication.

Claire L Gordon, Olivia C Smibert, Natasha E Holmes, Kyra YL Chua, Morgan Rose, George Drewett, Fiona James, Effie Mouhtouris, Thi HO Nguyen, Wuji Zhang, Lukasz Kedzierski, Louise C Rowntree, Brendon Y Chua, Leon Caly, Mike G Catton, Julian Druce, Michelle Sait, Torsten Seemann, Norelle L Sherry, Benjamin P Howden, et al.

Journal article  |  2021  |  Open Forum Infect Dis

We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune responses in a patient with lymphoma and ..

Accessible Platform for High-Throughput COVID-19 Molecular Diagnostics and Genome Sequencing Using a Repurposed 3D Printer for RNA Extraction.

Koen Vandelannoote, Andrew H Buultjens, Lucy Li, Liam K Sharkey, Marion Herisse, Sacha J Pidot, Tuyet Hoang, Benjamin P Howden, Ian R Monk, Torsten Seemann, Jean YH Lee, Timothy P Stinear

Journal article  |  2021  |  ACS Biomater Sci Eng

The COVID-19 pandemic has exposed the dependence of diagnostic laboratories on a handful of large corporations with market monopol..

Key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria: a systematic analysis

Claire L Gorrie, Anders Gonçalves Da Silva, Danielle J Ingle, Charlie Higgs, Torsten Seemann, Timothy P Stinear, Deborah A Williamson, Jason C Kwong, M Lindsay Grayson, Norelle L Sherry, Benjamin P Howden

Journal article  |  2021  |  The Lancet Microbe

Background Pairwise single nucleotide polymorphisms (SNPs) are a cornerstone of genomic approaches to the inference of transmissio..

Genomics-informed responses in the elimination of COVID-19 in Victoria, Australia: an observational, genomic epidemiological study

Courtney R Lane, Norelle L Sherry, Ashleigh F Porter, Sebastian Duchene, Kristy Horan, Patiyan Andersson, Mathilda Wilmot, Annabelle Turner, Sally Dougall, Sandra A Johnson, Michelle Sait, Anders Gonsalves da Silva, Susan A Ballard, Tuyet Hoang, Timothy P Stinear, Leon Caly, Vitali Sintchenko, Rikki Graham, Jamie McMahon, David Smith, et al.

Journal article  |  2021  |  LANCET PUBLIC HEALTH

BACKGROUND: A cornerstone of Australia's ability to control COVID-19 has been effective border control with an extensive supervise..

Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2.

Áine O'Toole, Verity Hill, Oliver G Pybus, Alexander Watts, Issac I Bogoch, Kamran Khan, Jane P Messina, undefined COVID-19 Genomics UK (COG-UK) consortium, undefined Network for Genomic Surveillance in South Africa (NGS-SA), undefined Brazil-UK CADDE Genomic Network, Houriiyah Tegally, Richard R Lessells, Jennifer Giandhari, Sureshnee Pillay, Kefentse Arnold Tumedi, Gape Nyepetsi, Malebogo Kebabonye, Maitshwarelo Matsheka, Madisa Mine, Sima Tokajian, et al.

Journal article  |  2021  |  Wellcome Open Res

Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of ..

Prolonged Outbreak of Multidrug-Resistant Shigella sonnei Harboring bla(CTX-M-27) in Victoria, Australia

Danielle J Ingle, Patiyan Andersson, Mary Valcanis, Jessica Barnden, Anders Goncalves da Silva, Kristy A Horan, Torsten Seemann, Marion Easton, Deborah A Williamson, Norelle L Sherry, Benjamin P Howden

Journal article  |  2020  |  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Australia, cases of shigellosis usually occur in returned travelers from regions of shigellosis endemicity or in men who have s..

Comprehensive Genomic Investigation of Adaptive Mutations Driving the Low-Level Oxacillin Resistance Phenotype in Staphylococcus aureus

Stefano G Giulieri, Romain Guerillot, Jason C Kwong, Ian R Monk, Ashleigh S Hayes, Diane Daniel, Sarah Baines, Norelle L Sherry, Natasha E Holmes, Peter Ward, Wei Gao, Torsten Seemann, Timothy P Stinear, Benjamin P Howden

Journal article  |  2020  |  MBIO

Antistaphylococcal penicillins such as oxacillin are the key antibiotics in the treatment of invasive methicillin-susceptible Stap..

Complete microbial genomes for public health in Australia and the Southwest Pacific

Sarah L Baines, Anders Goncalves da Silva, Glen P Carter, Amy Jennison, Irani Rathnayake, Rikki M Graham, Vitali Sintchenko, Qinning Wang, Rebecca J Rockett, Verlaine J Timms, Elena Martinez, Susan Ballard, Takehiro Tomita, Nicole Isles, Kristy A Horan, William Pitchers, Timothy P Stinear, Deborah A Williamson, Benjamin P Howden, Torsten Seemann

Journal article  |  2020  |  MICROBIAL GENOMICS

Complete genomes of microbial pathogens are essential for the phylogenomic analyses that increasingly underpin core public health ..

Case Report: Confirmation by Metagenomic Sequencing of Visceral Leishmaniasis in an Immunosuppressed Returned Traveler

Eloise Williams, Nicole S Isles, Torsten Seemann, Trevor Kilpatrick, Andrew Grigg, Marcel Leroi, Benjamin P Howden, Jason C Kwong

Journal article  |  2020  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

There has been increased interest in using metagenomic next-generation sequencing as an unbiased approach for diagnosing infectiou..