Torsten Seemann

Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria.

Andre Mu, William P Klare, Sarah L Baines, CN Ignatius Pang, Romain Guérillot, Nichaela Harbison-Price, Nadia Keller, Jonathan Wilksch, Nguyen Thi Khanh Nhu, Minh-Duy Phan, Bernhard Keller, Brunda Nijagal, Dedreia Tull, Saravanan Dayalan, Hwa Huat Charlie Chua, Dominik Skoneczny, Jason Koval, Abderrahman Hachani, Anup D Shah, Nitika Neha, et al.

Journal article  |  2023  |  Nat Commun

Even in the setting of optimal resuscitation in high-income countries severe sepsis and septic shock have a mortality of 20-40%, w..

Improved Genome Sequence of Australian Methicillin-Resistant Staphylococcus aureus Strain JKD6159

Ryan R Wick, Louise M Judd, Ian R Monk, Torsten Seemann, Timothy P Stinear

Journal article  |  2023  |  MICROBIOLOGY RESOURCE ANNOUNCEMENTS

Staphylococcus aureus strain JKD6159 represents a prominent community-acquired methicillin-resistant S. aureus (MRSA) clone in Aus..

An ISO-certified genomics workflow for identification and surveillance of antimicrobial resistance.

Norelle L Sherry, Kristy A Horan, Susan A Ballard, Anders Gonҫalves da Silva, Claire L Gorrie, Mark B Schultz, Kerrie Stevens, Mary Valcanis, Michelle L Sait, Timothy P Stinear, Benjamin P Howden, Torsten Seemann

Journal article  |  2023  |  Nat Commun

Realising the promise of genomics to revolutionise identification and surveillance of antimicrobial resistance (AMR) has been a lo..

State-wide genomic epidemiology investigations of COVID-19 in healthcare workers in 2020 Victoria, Australia: Qualitative thematic analysis to provide insights for future pandemic preparedness.

Anne E Watt, Norelle L Sherry, Patiyan Andersson, Courtney R Lane, Sandra Johnson, Mathilda Wilmot, Kristy Horan, Michelle Sait, Susan A Ballard, Christina Crachi, Dianne J Beck, Caroline Marshall, Marion A Kainer, Rhonda Stuart, Christian McGrath, Jason C Kwong, Pauline Bass, Peter G Kelley, Amy Crowe, Stephen Guy, et al.

Journal article  |  2022  |  Lancet Reg Health West Pac

BACKGROUND: COVID-19 has affected many healthcare workers (HCWs) globally. We performed state-wide SARS-CoV-2 genomic epidemiologi..

Genomic Evidence of In-Flight SARS-CoV-2 Transmission, India to Australia, April 2021.

Freya Hogarth, Pasqualina Coffey, Laura Goddard, Sarah Lewis, Shereen Labib, Mathilda Wilmot, Patiyan Andersson, Norelle Sherry, Torsten Seemann, Benjamin P Howden, Kevin Freeman, Robert Baird, Ian Hosegood, Kathleen McDermott, Nick Walsh, Ben Polkinghorne, Catherine Marshall, Jane Davies, Vicki Krause, Ella M Meumann

Journal article  |  2022  |  Emerg Infect Dis

Epidemiologic and genomic investigation of SARS-CoV-2 infections associated with 2 repatriation flights from India to Australia in..

Genomic characterisation reveals a dominant lineage of SARS-CoV-2 in Papua New Guinea

Theresa Palou, Mathilda Wilmot, Sebastian Duchene, Ashleigh Porter, Janlyn Kemoi, Dagwin Suarkia, Patiyan Andersson, Anne Watt, Norelle Sherry, Torsten Seemann, Michelle Sait, Charlie Turharus, Son Nguyen, Sanmarie Schlebusch, Craig Thompson, Jamie McMahon, Stefanie Vaccher, Chantel Lin, Danoi Esoram, Benjamin P Howden, et al.

Journal article  |  2022  |  VIRUS EVOLUTION

The coronavirus disease pandemic has highlighted the utility of pathogen genomics as a key part of comprehensive public health res..

Niche-specific genome degradation and convergent evolution shaping Staphylococcus aureus adaptation during severe infections

Stefano G Giulieri, Romain Guerillot, Sebastian Duchene, Abderrahman Hachani, Diane Daniel, Torsten Seemann, Joshua S Davis, Steven YC Tong, Bernadette C Young, Daniel J Wilson, Timothy P Stinear, Benjamin P Howden

Journal article  |  2022  |  ELIFE

During severe infections, Staphylococcus aureus moves from its colonising sites to blood and tissues and is exposed to new selecti..

SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

Wuji Zhang, Brendon Y Chua, Kevin J Selva, Lukasz Kedzierski, Thomas M Ashhurst, Ebene R Haycroft, Suzanne K Shoffner-Beck, Luca Hensen, David F Boyd, Fiona James, Effie Mouhtouris, Jason C Kwong, Kyra YL Chua, George Drewett, Ana Copaescu, Julie E Dobson, Louise C Rowntree, Jennifer R Habel, Lilith F Allen, Hui-Fern Koay, et al.

Journal article  |  2022  |  NATURE COMMUNICATIONS

Respiratory tract infection with SARS-CoV-2 results in varying immunopathology underlying COVID-19. We examine cellular, humoral a..

Multi-site implementation of whole genome sequencing for hospital infection control: A prospective genomic epidemiological analysis

Norelle L Sherry, Claire L Gorrie, Jason C Kwong, Charlie Higgs, Rhonda L Stuart, Caroline Marshall, Susan A Ballard, Michelle Sait, Tony M Korman, Monica A Slavin, Robyn S Lee, Maryza Graham, Marcel Leroi, Leon J Worth, Hiu Tat Chan, Torsten Seemann, M Lindsay Grayson, Benjamin P Howden

Journal article  |  2022  |  LANCET REGIONAL HEALTH-WESTERN PACIFIC

BACKGROUND: Current microbiological methods lack the resolution to accurately identify multidrug-resistant organism (MDRO) transmi..

AusTrakka: Fast-tracking nationalized genomics surveillance in response to the COVID-19 pandemic

Tuyet Hoang, Anders Goncalves da Silva, Amy Jennison, Deborah A Williamson, Benjamin P Howden, Torsten Seemann

Journal article  |  2022  |  NATURE COMMUNICATIONS

The COVID-19 pandemic has driven demand for integrated genomics, resulting in fast-tracked development of AusTrakka, Australia’s p..