Nichollas Scott

Open Database Searching Enables the Identification and Comparison of Bacterial Glycoproteomes without Defining Glycan Compositions Prior to Searching.

Ameera Raudah Ahmad Izaham, Nichollas E Scott

Journal article  |  2020  |  Molecular & Cellular Proteomics

Mass spectrometry has become an indispensable tool for the characterization of glycosylation across biological systems. Our abilit..

A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for diagnosis of glanders infections

Guanbo Wang, Lena Glaser, Nichollas Scott, Yasmine Fathy Mohamed, Rebecca Ingram, Karine Laroucau, Miguel Valvano

Journal article  |  2020

ABSTRACT We recently described a protein O -glycosylation pathway conserved in all species of the Burkholderia genus that results ..

The Salmonella Effector SseK3 Targets Small Rab GTPases

J Gan, NE Scott, JPM Newson, RR Wibawa, T Wong Fok Lung, GL Pollock, GZ Ng, I van Driel, JS Pearson, EL Hartland, C Giogha

Journal article  |  2020  |  Frontiers in Cellular and Infection Microbiology

A Sulfoglycolytic Entner-Doudoroff Pathway in Rhizobium leguminosarum bv. trifolii SRDI565

Jinling Li, Ruwan Epa, Nichollas E Scott, Dominik Skoneczny, Mahima Sharma, Alexander JD Snow, James P Lingford, Ethan D Goddard-Borger, Gideon J Davies, Malcolm J McConville, Spencer J Williams

Journal article  |  2020  |  Applied and Environmental Microbiology

Rhizobia are nitrogen-fixing bacteria that engage in symbiotic relationships with plant hosts but can also persist as free-living ..

What are we missing by using hydrophilic enrichment? Improving bacterial glycoproteome coverage using total proteome and FAIMS analysis

Ameera Raudah Ahmad Izaham, Ching-Seng Ang, Shuai Nie, Lauren Bird, Nicholas Williamson, Nichollas Scott

Journal article  |  2020

ABSTRACT Hydrophilic Interaction Liquid Chromatography (HILIC) glycopeptide enrichment is an indispensable tool for the high-throu..

Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19

Jennifer A Juno, Hyon-Xhi Tan, Wen Shi Lee, Arnold Reynaldi, Hannah G Kelly, Kathleen Wragg, Robyn Esterbauer, Helen E Kent, C Jane Batten, Francesca L Mordant, Nicholas A Gherardin, Phillip Pymm, Melanie H Dietrich, Nichollas E Scott, Wai-Hong Tham, Dale Godfrey, Kanta Subbarao, Miles P Davenport, Stephen J Kent, Adam K Wheatley

Journal article  |  2020  |  Nature Medicine

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has dramatically expedited global vaccine development ef..

Influence of Protein Glycosylation onCampylobacter fetusPhysiology

Justin Duma, Harald Nothaft, Danielle Weaver, Christopher Fodor, Bernadette Beadle, Dennis Linton, Stephane L Benoit, Nichollas E Scott, Robert J Maier, Christine M Szymanski

Journal article  |  2020  |  Frontiers in Microbiology

Proteomic identification of Coxiella burnetii effector proteins targeted to the host cell mitochondria during infection

Laura Fielden, Nichollas Scott, Catherine Palmer, Chen Ai Khoo, Hayley Newton, Diana Stojanovski

Journal article  |  2020

Abstract Modulation of the host cell is integral to the survival and replication of microbial pathogens. Several intracellular bac..

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity.

Zheng Fan, Jennifer R Devlin, Simon J Hogg, Maria A Doyle, Paul F Harrison, Izabela Todorovski, Leonie A Cluse, Deborah A Knight, Jarrod J Sandow, Gareth Gregory, Andrew Fox, Traude H Beilharz, Nicholas Kwiatkowski, Nichollas E Scott, Ana Tufegdzic Vidakovic, Gavin P Kelly, Jesper Q Svejstrup, Matthias Geyer, Nathanael S Gray, Stephin J Vervoort, et al.

Journal article  |  2020  |  Science advances

The RNA polymerase II (POLII)-driven transcription cycle is tightly regulated at distinct checkpoints by cyclin-dependent kinases ..

Open database searching enables the identification and comparison of bacterial glycoproteomes without defining glycan compositions prior to searching

Ameera Raudah Ahmad Izaham, Nichollas Scott

Journal article  |  2020

ABSTRACT Mass spectrometry has become an indispensable tool for the characterisation of glycosylation across biological systems. O..

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

Zheng Fan, Jennifer R Devlin, Simon J Hogg, Maria A Doyle, Paul F Harrison, Izabela Todorovski, Leonie A Cluse, Deborah A Knight, Jarrod J Sandow, Gareth Gregory, Andrew Fox, Traude H Beilharz, Nicholas Kwiatkowski, Nichollas E Scott, Ana Tufegdzic Vidakovic, Gavin P Kelly, Jesper Q Svejstrup, Matthias Geyer, Nathanael S Gray, Stephin J Vervoort, et al.

Journal article  |  2020  |  Science Advances

Biogenesis of the Spacious Coxiella-Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3

Bhavna Padmanabhan, Laura F Fielden, Abderrahman Hachani, Patrice Newton, David R Thomas, Hyun-Jung Cho, Chen Ai Khoo, Diana Stojanovski, Craig R Roy, Nichollas E Scott, Hayley J Newton

Journal article  |  2020  |  Infection and Immunity

Coxiella burnetii is an obligate intracellular bacterial pathogen that replicates inside the lysosome-derived Coxiella-containing ..

An intra-bacterial activity for a T3SS effector

Samir El Qaidi, Nichollas E Scott, Michael P Hays, Brian V Geisbrecht, Shelby Watkins, Philip R Hardwidge

Journal article  |  2020  |  Scientific Reports

Many Gram-negative bacterial pathogens interact with mammalian cells by using type III secretion systems (T3SS) to inject virulenc..

A sulfoglycolytic Entner-Doudoroff pathway in Rhizobium leguminosarum bv. trifolii SRDI565

Jinling Li, Ruwan Epa, Nichollas Scott, Dominic Skoneczny, Mahima Sharma, Alexander JD Snow, James Lingford, Ethan Goddard-Borger, Gideon Davies, Malcolm McConville, Spencer Williams

Journal article  |  2019

Abstract Rhizobia are nitrogen fixing bacteria that engage in symbiotic relationships with plant hosts but can also persist as fre..

Trefoil factors share a lectin activity that defines their role in mucus

Michael Järvå, James Lingford, Alan John, Nichollas Scott, Ethan Goddard-Borger

Journal article  |  2019

The trefoil factors (TFFs) are disulfide-rich mucosal peptides that protect the epithelium by promoting cell migration and increas..

Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators

Cameron C Oppy, Leila Jebeli, Miku Kuba, Clare V Oates, Richard Strugnell, Laura E Edgington-Mitchell, Miguel A Valvano, Elizabeth L Hartland, Hayley J Newton, Nichollas E Scott

Journal article  |  2019  |  mSphere

O-linked protein glycosylation is a conserved feature of the Burkholderia genus. The addition of the trisaccharide β-Gal-(1,3)-α-G..

Low pH Exposure During Immunoglobulin G Purification Methods Results in Aggregates That Avidly Bind Fcg Receptors: Implications for Measuring Fc Dependent Antibody Functions

Ester Lopez, Nichollas E Scott, Bruce D Wines, P Mark Hogarth, Adam K Wheatley, Stephen J Kent, Amy W Chung

Journal article  |  2019  |  FRONTIERS IN IMMUNOLOGY

Evaluating the biophysical and functional nature of IgG is key to defining correlates of protection in infectious disease, and aut..

Peptidyl-Prolyl Isomerase ppiB Is Essential for Proteome Homeostasis and Virulence in Burkholderia pseudomallei

Nicole M Bzdyl, Nichollas E Scott, Isobel H Norville, Andrew E Scott, Timothy Atkins, Stanley Pang, Derek S Sarovich, Geoffrey Coombs, Timothy JJ Inglis, Charlene M Kahler, Mitali Sarkar-Tyson

Journal article  |  2019  |  Infection and Immunity

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis

Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, et al.

Journal article  |  2019  |  iScience

Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and di..

A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae

Mario F Feldman, Anne E Mayer Bridwell, Nichollas E Scott, Evgeny Vinogradov, Samuel R McKee, Sthefany M Chavez, Joy Twentyman, Christina L Stallings, David A Rosen, Christian M Harding

Journal article  |  2019  |  Proceedings of the National Academy of Sciences

A general protein O-glycosylation machinery conserved in Burkholderia species improves bacterial fitness and elicits glycan immunogenicity in humans

Yasmine Fathy Mohamed, Nichollas E Scott, Antonio Molinaro, Carole Creuzenet, Ximena Ortega, Ganjana Lertmemongkolchai, Michael M Tunney, Heather Green, Andrew M Jones, David DeShazer, Bart J Currie, Leonard J Foster, Rebecca Ingram, Cristina De Castro, Miguel A Valvano

Journal article  |  2019  |  Journal of Biological Chemistry

The Burkholderia genus encompasses many Gram-negative bacteria living in the rhizosphere. Some Burkholderia species can cause life..

Loss of O-linked protein glycosylation in Burkholderia cenocepacia impairs biofilm formation and siderophore production via alteration of quorum sensing regulation

Cameron Oppy, Leila Jebeli, Miku Kuba, Clare Oates, Richard Strugnell, Laura Edgington-Mitchell, Miguel Valvano, Elizabeth Hartland, Hayley Newton, Nichollas Scott

Journal article  |  2019

Abstract O -linked protein glycosylation is a conserved feature of the Burkholderia genus. For Burkholderia cenocepacia , the addi..

Expanding our understanding of the role of microbial glycoproteomes through high-throughput mass spectrometry approaches

Nichollas E Scott

Journal article  |  2019  |  Glycoconjugate Journal

Protein glycosylation is increasingly recognised as an essential requirement for effective microbial infections. Within microbial ..

Profiling the Escherichia coli membrane protein interactome captured in Peptidisc libraries

Michael Luke Carlson, R Greg Stacey, John William Young, Irvinder Singh Wason, Zhiyu Zhao, David G Rattray, Nichollas Scott, Craig H Kerr, Mohan Babu, Leonard J Foster, Franck Duong Van Hoa

Journal article  |  2019  |  eLife

Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes

Gisela Di Venanzio, Ana L Flores-Mireles, Juan J Calix, M Florencia Haurat, Nichollas E Scott, Lauren D Palmer, Robert F Potter, Michael E Hibbing, Laura Friedman, Bin Wang, Gautam Dantas, Eric P Skaar, Scott J Hultgren, Mario F Feldman

Journal article  |  2019  |  Nature Communications

Multidrug resistant (MDR) Acinetobacter baumannii poses a growing threat to global health. Research on Acinetobacter pathogenesis ..

Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways

Joshua PM Newson, Nichollas E Scott, Ivy Yeuk Wah Chung, Tania Wong Fok Lung, Cristina Giogha, Jiyao Gan, Nancy Wang, Richard A Strugnell, Nathaniel F Brown, Miroslaw Cygler, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2019  |  Molecular & Cellular Proteomics

Proteomics Reveals Multiple Phenotypes Associated with N-linked Glycosylation in Campylobacter jejuni

Joel A Cain, Ashleigh L Dale, Paula Niewold, William P Klare, Lok Man, Melanie Y White, Nichollas E Scott, Stuart J Cordwell

Journal article  |  2019  |  Molecular & Cellular Proteomics

Campylobacter jejuni is a major gastrointestinal pathogen generally acquired via consumption of poorly prepared poultry. N-linked ..

Characterization of the Citrobacter rodentium Cpx regulon and its role in host infection

Stefanie L Vogt, Roland Scholz, Yun Peng, Randi L Guest, Nichollas E Scott, Sarah E Woodward, Leonard J Foster, Tracy L Raivio, B Brett Finlay

Journal article  |  2019  |  Molecular Microbiology

Envelope-localized proteins, such as adhesins and secretion systems, play critical roles in host infection by Gram-negative pathog..

A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host

Christian M Harding, Mohamed A Nasr, Nichollas E Scott, Guillaume Goyette-Desjardins, Harald Nothaft, Anne E Mayer, Sthefany M Chavez, Jeremy P Huynh, Rachel L Kinsella, Christine M Szymanski, Christina L Stallings, Mariela Segura, Mario F Feldman

Journal article  |  2019  |  Nature Communications

Chemical synthesis of conjugate vaccines, consisting of a polysaccharide linked to a protein, can be technically challenging, and ..

Protein O-fucosyltransferase 2-mediated O-glycosylation of the adhesin MIC2 is dispensable for Toxoplasma gondii tachyzoite infection

Sachin Khurana, Michael J Coffey, Alan John, Alessandro D Uboldi, My-Hang Huynh, Rebecca J Stewart, Vern B Carruthers, Christopher J Tonkin, Ethan D Goddard-Borger, Nichollas E Scott

Journal article  |  2019  |  Journal of Biological Chemistry

GLYCOSYLATION OF PLASMODIUM FALCIPARUM THROMBOSPONDIN REPEATS DRIVES MOSQUITO TRANSMISSION AND SPOROZOITE VIRULENCE

Sash Lopaticki, Charlie Jennison, Nichollas Scott, Alan John, Annie Yang, Matthew O'Neill, Norman Kneteman, Ethan Goddard-Borger, Justin Boddey

Conference Proceedings  |  2019  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

An essential mitochondrial fucosyltransferase in Leishmania parasites

Gloria Polanco, Hongjie Guo, Stefanie Menzies, Nichollas E Scott, Sebastian Damerow, Hicham Zegzouti, Michael AJ Ferguson, Stephen M Beverley

Conference Proceedings  |  2018  |  GLYCOBIOLOGY

Transmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cells

Craig H Kerr, Udit Dalwadi, Nichollas E Scott, Calvin K Yip, Leonard J Foster, Eric Jan

Journal article  |  2018  |  Scientific Reports

Surface Exposure and Packing of Lipoproteins into Outer Membrane Vesicles Are Coupled Processes in Bacteroides

Ezequiel Valguarnera, Nichollas E Scott, Philippe Azimzadeh, Mario F Feldman

Journal article  |  2018  |  mSphere

Outer membrane vesicles (OMVs) are spherical structures derived from the outer membranes (OMs) of Gram-negative bacteria. Bacteroi..

Synthesis and use of 6,6,6-trifluoro-L-fucose to block core-fucosylation in hybridoma cell lines

Nicole C McKenzie, Nichollas E Scott, Alan John, Jonathan M White, Ethan D Goddard-Borger

Journal article  |  2018  |  Carbohydrate Research

Cost-effectiveness of the controlled temperature chain for the hepatitis B birth dose vaccine in a variety of global settings

N Scott, A Palmer, C Morgan, O Lesi, CW Spearman, M Sonderup, M Hellard

Conference Proceedings  |  2018  |  JOURNAL OF VIRAL HEPATITIS

Preliminary analysis of the Prime Study; A randomized controlled trial comparing the hepatitis C care cascade in primary care vs. tertiary care

A Wade, J Doyle, E Gane, C Stedman, B Draper, D Iser, S Roberts, W Kemp, D Petrie, N Scott, P Higgs, P Agius, J Roney, L Stothers, A Thompson, M Hellard

Conference Proceedings  |  2018  |  Journal of Hepatology

Post-translational Mechanisms of Host Subversion by Bacterial Effectors

Nichollas E Scott, Elizabeth L Hartland

Journal article  |  2017  |  Trends in Molecular Medicine

A rapid and accurate approach for prediction of interactomes from co-elution data (PrInCE)

R Greg Stacey, Michael A Skinnider, Nichollas E Scott, Leonard J Foster

Journal article  |  2017  |  BMC Bioinformatics

The bacterial arginine glycosyltransferase effector NleB preferentially modifies Fas-associated death domain protein (FADD)

Nichollas E Scott, Cristina Giogha, Georgina L Pollock, Catherine L Kennedy, Andrew I Webb, Nicholas A Williamson, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2017  |  Journal of Biological Chemistry

Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts

Sash Lopaticki, Annie SP Yang, Alan John, Nichollas E Scott, James P Lingford, Matthew T O'Neill, Sara M Erickson, Nicole C McKenzie, Charlie Jennison, Lachlan W Whitehead, Donna N Douglas, Norman M Kneteman, Ethan D Goddard-Borger, Justin A Boddey

Journal article  |  2017  |  Nature Communications

The role of mass spectrometry analysis in bacterial effector characterization

Nichollas E Scott, Elizabeth L Hartland

Journal article  |  2017  |  Biochemical Journal

Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems

Christian M Harding, Marina R Pulido, Gisela Di Venanzio, Rachel L Kinsella, Andrew I Webb, Nichollas E Scott, Jeronimo Pachon, Mario F Feldman

Journal article  |  2017  |  Journal of Biological Chemistry

Interactome disassembly during apoptosis occurs independent of caspase cleavage

Nichollas E Scott, Lindsay D Rogers, Anna Prudova, Nat F Brown, Nikolaus Fortelny, Christopher M Overall, Leonard J Foster

Journal article  |  2017  |  Molecular Systems Biology

Characterizing Glycoproteins by Mass Spectrometry in Campylobacter jejuni

Nichollas E Scott

Book Chapter  |  2017  |  Methods in Molecular Biology

Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase

Michael J Bround, Rich Wambolt, Haoning Cen, Parisa Asghari, Razvan F Albu, Jun Han, Donald McAfee, Marc Pourrier, Nichollas E Scott, Lubos Bohunek, Jerzy E Kulpa, SR Wayne Chen, David Fedida, Roger W Brownsey, Christoph H Borchers, Leonard J Foster, Thibault Mayor, Edwin DW Moore, Michael F Allard, James D Johnson

Journal article  |  2016  |  Journal of Biological Chemistry

Genetic Dissection of the Type VI Secretion System in Acinetobacter and Identification of a Novel Peptidoglycan Hydrolase, TagX, Required for Its Biogenesis

Brent S Weber, Seth W Hennon, Meredith S Wright, Nichollas E Scott, Veronique de Berardinis, Leonard J Foster, Juan A Ayala, Mark D Adams, Mario F Feldman

Journal article  |  2016  |  mBio

Protein O-linked glycosylation in the plant pathogen Ralstonia solanacearum

Wael Elhenawy, Nichollas E Scott, M Laura Tondo, Elena G Orellano, Leonard J Foster, Mario F Feldman

Journal article  |  2016  |  Glycobiology

High-Frequency Variation of Purine Biosynthesis Genes Is a Mechanism of Success in Campylobacter jejuni

Andrew Cameron, Steven Huynh, Nichol Las E Scott, Emilisa Frirdich, Dmitry Apel, Leonard J Foster, Craig T Parker, Erin C Gaynor

Journal article  |  2015  |  mBio

Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation

Gesa Volkers, Liam J Worrall, David H Kwan, Ching-Ching Yu, Lars Baumann, Emilie Lameignere, Gregory A Wasney, Nichollas E Scott, Warren Wakarchuk, Leonard J Foster, Stephen G Withers, Natalie CJ Strynadka

Journal article  |  2015  |  Nature Structural & Molecular Biology

Novel Host Proteins and Signaling Pathways in Enteropathogenic E. coli Pathogenesis Identified by Global Phosphoproteome Analysis

Roland Scholz, Koshi Imami, Nichollas E Scott, William S Trimble, Leonard J Foster, B Brett Finlay

Journal article  |  2015  |  Molecular & Cellular Proteomics

Acinetobacter strains carry two functional oligosaccharyltransferases, one devoted exclusively to type IV pilin, and the other one dedicated to O-glycosylation of multiple proteins

Christian M Harding, Mohamed A Nasr, Rachel L Kinsella, Nichollas E Scott, Leonard J Foster, Brent S Weber, Steve E Fiester, Luis A Actis, Erin N Tracy, Robert S Munson, Mario F Feldman

Journal article  |  2015  |  Molecular Microbiology

Development of a computational framework for the analysis of protein correlation profiling and spatial proteomics experiments

Nichollas E Scott, Lyda M Brown, Anders R Kristensen, Leonard J Foster

Journal article  |  2015  |  Journal of Proteomics

Clinical implications of glycoproteomics for Acinetobacter baumannii

Rachel L Kinsella, Nichollas E Scott, Mario F Feldman

Journal article  |  2015  |  Expert Review of Proteomics

Enrichment and Identification of Bacterial Glycopeptides by Mass Spectrometry

Nichollas E Scott, Stuart J Cordwell

Journal article  |  2015  |  Methods in Molecular Biology

Comparative Proteomics and Glycoproteomics Reveal Increased N-Linked Glycosylation and Relaxed Sequon Specificity in Campylobacter jejuni NCTC11168 O

Nichollas E Scott, N Bishara Marzook, Joel A Cain, Nestor Solis, Morten Thaysen-Andersen, Steven P Djordjevic, Nicolle H Packer, Martin R Larsen, Stuart J Cordwell

Journal article  |  2014  |  Journal of Proteome Research

Diversity Within the O-linked Protein Glycosylation Systems of Acinetobacter Species

Nichollas E Scott, Rachel L Kinsella, Alistair VG Edwards, Martin R Larsen, Sucharita Dutta, Julian Saba, Leonard J Foster, Mario F Feldman

Journal article  |  2014  |  Molecular & Cellular Proteomics

A general protein O-glycosylation system within the Burkholderia cepacia complex is involved in motility and virulence

Karen V Lithgow, Nichollas E Scott, Jeremy A Iwashkiw, Euan LS Thomson, Leonard J Foster, Mario F Feldman, Jonathan J Dennis

Journal article  |  2014  |  Molecular Microbiology

Secretome of Transmissible Pseudomonas aeruginosa AES-1R Grown in a Cystic Fibrosis Lung-Like Environment

Nichollas E Scott, Nathan J Hare, Melanie Y White, Jim Manos, Stuart J Cordwell

Journal article  |  2013  |  Journal of Proteome Research

Site-Specific Glycan-Peptide Analysis for Determination of N-Glycoproteome Heterogeneity

Benjamin L Parker, Morten Thaysen-Andersen, Nestor Solis, Nichollas E Scott, Martin R Larsen, Mark E Graham, Nicolle H Packer, Stuart J Cordwell

Journal article  |  2013  |  Journal of Proteome Research

A common pathway for O-linked protein-glycosylation and synthesis of capsule in Acinetobacter baumannii

Robert G Lees-Miller, Jeremy A Iwashkiw, Nichollas E Scott, Andrea Seper, Evgeny Vinogradov, Stefan Schild, Mario F Feldman

Journal article  |  2013  |  Molecular Microbiology

In Vitro Activity of Neisseria meningitidis PglL O-Oligosaccharyltransferase with Diverse Synthetic Lipid Donors and a UDP-activated Sugar

Matias A Musumeci, Isabelle Hug, Nichollas E Scott, M Veronica Ielmini, Leonard J Foster, Peng G Wang, Mario F Feldman

Journal article  |  2013  |  Journal of Biological Chemistry

Diversity in the Protein N-Glycosylation Pathways Within the Campylobacter Genus

Harald Nothaft, Nichollas E Scott, Evgeny Vinogradov, Xin Liu, Rui Hu, Bernadette Beadle, Christopher Fodor, William G Miller, Jianjun Li, Stuart J Cordwell, Christine M Szymanski

Journal article  |  2012  |  Molecular & Cellular Proteomics

Modification of the Campylobacter jejuni N-Linked Glycan by EptC Protein-mediated Addition of Phosphoethanolamine

Nichollas E Scott, Harald Nothaft, Alistair VG Edwards, Maurizio Labbate, Steven P Djordjevic, Martin R Larsen, Christine M Szymanski, Stuart J Cordwell

Journal article  |  2012  |  Journal of Biological Chemistry

Identification of a General O-linked Protein Glycosylation System in Acinetobacter baumannii and Its Role in Virulence and Biofilm Formation

Jeremy A Iwashkiw, Andrea Seper, Brent S Weber, Nichollas E Scott, Evgeny Vinogradov, Chad Stratilo, Bela Reiz, Stuart J Cordwell, Randy Whittal, Stefan Schild, Mario F Feldman

Journal article  |  2012  |  PLoS Pathogens

Sequence TTKF down arrow QE Defines the Site of Proteolytic Cleavage in Mhp683 Protein, a Novel Glycosaminoglycan and Cilium Adhesin of Mycoplasma hyopneumoniae

Daniel R Bogema, Nichollas E Scott, Matthew P Padula, Jessica L Tacchi, Benjamin BA Raymond, Cheryl Jenkins, Stuart J Cordwell, F Chris Minion, Mark J Walker, Steven P Djordjevic

Journal article  |  2011  |  Journal of Biological Chemistry

Quantitative N-linked Glycoproteomics of Myocardial Ischemia and Reperfusion Injury Reveals Early Remodeling in the Extracellular Environment

Benjamin L Parker, Giuseppe Palmisano, Alistair VG Edwards, Melanie Y White, Kasper Engholm-Keller, Albert Lee, Nichollas E Scott, Daniel Kolarich, Brett D Hambly, Nicolle H Packer, Martin R Larsen, Stuart J Cordwell

Journal article  |  2011  |  Molecular & Cellular Proteomics

Proteomics of the oxidative stress response induced by hydrogen peroxide and paraquat reveals a novel AhpC-like protein in Pseudomonas aeruginosa

Nathan J Hare, Nichollas E Scott, Eun Hye H Shin, Angela M Connolly, Martin R Larsen, Giuseppe Palmisano, Stuart J Cordwell

Journal article  |  2011  |  PROTEOMICS

Simultaneous Glycan-Peptide Characterization Using Hydrophilic Interaction Chromatography and Parallel Fragmentation by CID, Higher Energy Collisional Dissociation, and Electron Transfer Dissociation MS Applied to the N-Linked Glycoproteome of Campylobacter jejuni

Nichollas E Scott, Benjamin L Parker, Angela M Connolly, Jana Paulech, Alistair VG Edwards, Ben Crossett, Linda Falconer, Daniel Kolarich, Steven P Djordjevic, Peter Hojrup, Nicolle H Packer, Martin R Larsen, Stuart J Cordwell

Journal article  |  2011  |  Molecular & Cellular Proteomics

Mass spectrometric characterization of the Campylobacter jejuni adherence factor CadF reveals post-translational processing that removes immunogenicity while retaining fibronectin binding

Nichollas E Scott, N Bishara Marzook, Ania Deutscher, Linda Falconer, Ben Crossett, Steven P Djordjevic, Stuart J Cordwell

Journal article  |  2010  |  PROTEOMICS

Mass Spectrometric Characterization of the Surface-Associated 42 kDa Lipoprotein JlpA as a Glycosylated Antigen in Strains of Campylobacter jejuni

Nichollas E Scott, Daniel R Bogema, Angela M Connolly, Linda Falconer, Steven P Djordjevic, Stuart J Cordwell

Journal article  |  2009  |  Journal of Proteome Research

Campylobacter proteomics: guidelines, challenges and future perspectives

Nichollas E Scott, Stuart J Cordwell

Journal article  |  2009  |  Expert Review of Proteomics

Identification of membrane-associated proteins from Campylobacter jejuni strains using complementary proteomics technologies

Stuart J Cordwell, CL Len Alice, Rachel G Touma, Nichollas E Scott, Linda Falconer, David Jones, Angela Connolly, Crossett Ben, Steven P Djordjevic

Journal article  |  2008  |  PROTEOMICS

Direct RNA sequencing and early evolution of SARS-CoV-2

George Taiaroa, Daniel Rawlinson, Leo Featherstone, Miranda Pitt, Leon Caly, Julian Druce, Damian Purcell, Leigh Harty, Thomas Tran, Jason Roberts, Nichollas Scott, Mike Catton, Deborah Williamson, Lachlan Coin, Sebastian Duchene

Journal article

AbstractFundamental aspects of SARS-CoV-2 biology remain to be described, having the potential to provide insight to the response ..