Behnaz Heydarchi

Enhancement of Antibody-Dependent Cellular Cytotoxicity and Phagocytosis in Anti-HIV-1 Human-Bovine Chimeric Broadly Neutralizing Antibodies.

Jack M Edwards, Behnaz Heydarchi, Georges Khoury, Natalia A Salazar-Quiroz, Christopher A Gonelli, Bruce Wines, P Mark Hogarth, Anne B Kristensen, Matthew S Parsons, Damian FJ Purcell

Journal article  |  2021  |  J Virol

No prophylactic vaccine has provided robust protection against human immunodeficiency virus type 1 (HIV-1). Vaccine-induced broadl..

HIV-1 Env Trimers Eliciting Antibody With Neutralising and Cellular-dependent Functions in Vaccinated Cows

Damian Purcell, Natalia Salazar-Quiroz, Jack Edwards, Brian Muller, Chris Gonelli, Charlene MacKenzie, Georges Khoury, David MacInnes, Behnaz Heydarchi

Conference Proceedings  |  2018  |  AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV Neutralising Monoclonal Antibodies With Optimised Antibody Effector Functions

Behnaz Heydarchi, Jack Edwards, Christopher Gonelli, Damian Purcell

Conference Proceedings  |  2018  |  AIDS RESEARCH AND HUMAN RETROVIRUSES

Trimeric gp120-specific bovine monoclonal antibodies require cysteine and aromatic residues in CDRH3 for high affinity binding to HIV Env

Behnaz Heydarchi, Rob J Center, Jonathan Bebbington, Jack Cuthbertson, Christopher Gonelli, Georges Khoury, Charlene Mackenzie, Marit Lichtfuss, Grant Rawlin, Brian Muller, Damian Purcell

Journal article  |  2017  |  MABS

We isolated HIV-1 Envelope (Env)-specific memory B cells from a cow that had developed high titer polyclonal immunoglobulin G (IgG..

Repeated Vaccination of Cows with HIV Env gp140 during Subsequent Pregnancies Elicits and Sustains an Enduring Strong Env-Binding and Neutralising Antibody Response

Behnaz Heydarchi, Rob J Center, Christopher Gonelli, Brian Muller, Charlene Mackenzie, Georges Khoury, Marit Lichtfuss, Grant Rawlin, Damian FJ Purcell

Journal article  |  2016  |  PLOS ONE

An important feature of a potential vaccine against HIV is the production of broadly neutralising antibodies (BrNAbs) capable of p..

Chimeric Bovine-V-region and Human-C-region mAbs with Long and Extensively Mutated CDHR3 Domains Bind HIV-1 Env gp140 Trimers, but Not gp120 Monomer

Behnaz Heydarchi, Robert Center, undefined Ramarathinam, Christopher Gonelli, Brian Muller, Charlene Mackenzie, Jack Cuthbertson, Marit Kramski, Damian FJ Purcell

Conference Proceedings  |  2014  |  AIDS RESEARCH AND HUMAN RETROVIRUSES

Expression of the influenza M2 protein in three different eukaryotic cell lines

Maryam Esghaei, Seyed Hamid Reza Monavari, Masoumeh Tavassoti-Kheiri, Mahmoud Shamsi-Shahrabadi, Behnaz Heydarchi, Behrokh Farahmand, Maryam Saleh, Fatemeh Fotouhi

Journal article  |  2012  |  JOURNAL OF VIROLOGICAL METHODS

Current influenza virus vaccines provide protection in part by antibodies induced to the two surface glycoproteins, the hemaggluti..

Phylogenetic Comparison of Influenza Virus Isolates from Three Medical Centers in Tehran with the Vaccine Strains during 2008-2009.

Seyedeh Fahime Mousavi, Masoumeh Tavassoti Kheiri, Seyed Masoud Hosseini, Mojgan Taghizadeh, Fatemeh Fotouhi, Behnaz Heydarchi, Rouzbeh Bashar, Hosna Gomari

Journal article  |  2011  |  Iran J Med Sci

BACKGROUND: Influenza virus is a major infectious pathogen of the respiratory system causing a high degree of morbidity and mortal..