Sarah Diepstraten

MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3( )regulatory T cells

Charis E Teh, Alissa K Robbins, Darren C Henstridge, Grant Dewson, Sarah T Diepstraten, Gemma Kelly, Mark A Febbraio, Sarah S Gabriel, Lorraine A O'Reilly, Andreas Strasser, Daniel HD Gray

Journal article  |  2020  |  Cell Death & Differentiation

FOXP3+ regulatory T (Treg) cells are essential for maintaining immunological tolerance. Given their importance in immune-related d..

Strip and Cka negatively regulate JNK signalling during Drosophila spermatogenesis

John E La Marca, Sarah T Diepstraten, Amy L Hodge, Hongyan Wang, Adam H Hart, Helena E Richardson, W Gregory Somers

Journal article  |  2019  |  Development

One fundamental property of a stem cell niche is the exchange of molecular signals between its component cells. Niche models, such..

Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development

Brandon J Aubrey, Ana Janic, Yunshun Chen, Catherine Chang, Elizabeth C Lieschke, Sarah T Diepstraten, Andrew J Kueh, Jonathan P Bernardini, Grant Dewson, Lorraine A O'Reilly, Lachlan Whitehead, Anne K Voss, Gordon K Smyth, Andreas Strasser, Gemma L Kelly

Journal article  |  2018  |  Genes & Development